Welcome to the Chalasani lab! We use Caenorhabditis elegans, Danio rerio, and Mus musculus to study how the nervous system integrates changes in external and internal environment to generate behavior. We expect to uncover principles of brain function and develop therapeutics for various human neurological conditions.
Pribadi, A., Rieger, M.A., Rosales, K., Reddy, K.C., Chalasani, S.H. Dopamine signaling regulates predator-driven changes in egg laying behavior. (2023) Elife. 12. DOI: 10.7554/eLife.83957
Procko, C., Wong, W.M., Patel, J., Mousavi, S.A.R., Dabi, T., Duque, M., Baird, L., Chalasani, S.H., Chory, J. Mutational analysis of mechanosensitive ion channels in the carnivorous Venus flytrap plant. (2023) Current Biology. DOI: 10.1016/j.cub.2023.06.048
Magaram, U., Weiss, C., Vasan, A., Reddy, K.C., Friend, J., Chalasani, S.H. Two pathways are required for ultrasound-evoked behavioral changes in Caenorhabditis elegans. (2022) PLOS One. 17(5):e0267698. DOI: 10.1371/journal.pone.0267698
Matty, M.A., Lau, H.E., Haley, J.A., Singh, A., Chakraborty, A., Kono, K., Reddy, K.C., Hansen, M., Chalasani, S.H. Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans. (2022) PLOS Genetics. 18(5):e1010178. DOI: 10.1371/journal.pgen.1010178
Mei, J., Vasan, A., Magaram, U., Takemura, K., Chalasani, S.H., Friend, J. Well-free agglomeration and on-demand three-dimensional cell cluster formation using guided surface acoustic waves through a couplant layer. (2022) Biomed Microdevices. 24(2):18. DOI: 10.1007/s10544-022-00617-z