Welcome

Welcome to the Chalasani lab! We use Caenorhabditis elegans, Danio rerio, and Mus musculus to study how the nervous system integrates changes in external and internal environment to generate behavior. We expect to uncover principles of brain function and develop therapeutics for various human neurological conditions.

Recent Publications


Haley, J.A., Chen, T., Aoi, M., Chalasani, S.H. Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging (2025) Elife. 13. DOI: 10.7554/eLife.103191

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Mackie, M., Le, V.V., Carstensen, H.R., Kushnir, N.R., Castro, D.L., Dimov, I.M., Quach, K.T., Cook, S.J., Hobert, O., Chalasani, S.H., Hong, R.L. Evolution of lateralized gustation in nematodes. (2025) Elife. 14. DOI: 10.7554/eLife.103796

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Haley, J.A., Chen, T., Aoi, M., Chalasani, S.H. Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging (2025) bioRxiv. DOI: 10.1101/2024.09.18.613674

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Rusu, I., Cecere, Z.T., How, J.J., Quach, K.T., Yemini, E., Sharpee, T.O., Chalasani, S.H. A framework for analyzing C. elegans neural activity using multi-dimensional hyperbolic embedding (2025) bioRxiv. DOI: 10.1101/2021.04.09.439242

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Quach, K.T., Hughes, G.A., Chalasani, S.H. Interdependence between SEB-3 receptor and NLP-49 peptides shifts across predator-induced defensive behavioral modes in Caenorhabditis elegans (2025) Elife. 13. DOI: 10.7554/eLife.98262

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