Welcome to the Chalasani lab! We use Caenorhabditis elegans, Danio rerio, and Mus musculus to study how the nervous system integrates changes in external and internal environment to generate behavior. We expect to uncover principles of brain function and develop therapeutics for various human neurological conditions.
Rusu, I., Cecere, Z.T., How, J.J., Quach, K.T., Yemini, E., Sharpee, T.O., Chalasani, S.H. A framework for analyzing neural activity using multi-dimensional hyperbolic embedding. (2025) bioRxiv. DOI: 10.1101/2021.04.09.439242
Quach, K.T., Hughes, G.A., Chalasani, S.H. Interdependence between SEB-3 receptor and NLP-49 peptides shifts across predator-induced defensive behavioral modes in . (2025) Elife. 13. DOI: 10.7554/eLife.98262
Shukla, S., Schwartz, J.L., Walsh, C., Wong, W.M., Patel, V., Hsieh, Y.P., Onwuasoanya, C., Chen, S., Offenhäusser, A., Cauwenberghs, G., Santoro, F., Muotri, A.R., Yeo, G.W., Chalasani, S.H., Jahed, Z. Supra- and sub-threshold intracellular-like recording of 2D and 3D neuronal networks using nanopillar electrode arrays. (2024) Microsyst Nanoeng. 10(1):184. DOI: 10.1038/s41378-024-00817-y
Cowen, M.H., Haskell, D., Zoga, K., Reddy, K.C., Chalasani, S.H., Hart, M.P. Conserved autism-associated genes tune social feeding behavior in C. elegans. (2024) Nature Communications. 15(1):9301. DOI: 10.1038/s41467-024-53590-x
Mackie, M., Le, V.V., Carstensen, H.R., Kushnir, N.R., Castro, D.L., Dimov, I.M., Quach, K.T., Cook, S.J., Hobert, O., Chalasani, S.H., Hong, R.L. Evolution of lateralized gustation in nematodes. (2024) bioRxiv. DOI: 10.1101/2024.08.31.610597